autism

Almost exactly a year ago, I noted the very sad case of Jeremy LaBrie, an 8 year old autistic child with non-Hodgkin's lymphoma whose mother Kristen withheld his medications and failed to take him to appointments with his oncologist. As a result of his failing to undergo his complete course of chemotherapy, his cancer returned with a vengeance. As of one year ago, his odds of survival were estimated to be no more than 10-20%, after having had a good prognosis when initially diagnosed. At the time, I thought it was entirely appropriate for the state to prosecute Kristen LaBrie for medical…
Blogging is usually such an instant gratification sort of thing. I see a story or hear about something. I write about it. I almost have to. Most stories in the blogosphere have a really short half-life anyway. Wait more than a day or two, and no one cares anymore. Hell, wait more than a few hours in the case of hyperkinetic bloggers like P.Z. will be all over it. However, sometimes it's a good idea to restrain myself, not to leap on something right away even when I can. This is one of those times. Last week, I was tipped off by the merry band of anti-vaccine loons over at Age of Autism to a…
If there's one thing that I've found that's simultaneously gratifying and somewhat infuriating over the last year or so, it's that the skeptical movement has finally really noticed that anti-vaccination movement in a big way. Those of us who've been on the blogospheric front lines for the last few years have sometimes been frustrated that this issue, at least until recently, got so little attention outside of our dedicated little circle and the much larger circle of anti-vaccine zealots and the quacks who enable and encourage them. That's not to say that there weren't some prominent skeptics…
The new study identifies 27 loci that have rare copy number variations, where there are more or fewer repeated DNA segments than expected, common to the genomes of several children with autism spectrum disorder. These variations are not present in controls without autism spectrum disorder. The peer reviewed paper is available in the Open Access journal PLoS Genetics. The sample included 2,832 individuals distributed among 912 families that had multiple autistic children. The control group consisted of 1,070 samples of disease-free children who presumably are not clustered from a smaller…
Here we go again. You may have noticed that I've been laying off that repository of quackery, autism pseudoscience, and anti-vaccine nonsense, The Huffington Post. I assure you, it's not because things have gotten much better there. Oh, sure, occasionally someone will try to post something resembling science and rationality, but it's impossible for so few to overcome so much history and so much woo. Indeed, even when someone tries, he can't help but be sucked into the morass of pseudoscience that is HuffPo. For example, Dr. Harvey Karp (the same guy who went toe-to-toe with Dr. Jay Gordon--…
"Empowerment." What a grand word! After all, who doesn't want to be "empowered"? Certainly not me. Perhaps that's the reason why it's become the new buzzword in a movement known as "patient-centered" care. Old fart that I am, I'm a bit puzzled by exactly what that term means. After all, I've always thought I have been practicing patient-centered care, ever since my first days in medical school, but apparently these days it means something different, at least if this article from a few days ago in the New York Times is any indication. It's an interview with Dr. Donald Berwick, who advocates…
Dr. Jay is back. You remember Dr. Jay (namely Dr. Jay "I'm not anti-vaccine but I give vaccines only 'reluctantly' and am convinced that they cause autism" Gordon), pediatrician to Evan, Jenny McCarthy's son and frequent apologist for the antivaccine movement in the media. Specifically, he was most unhappy over my posts about Dr. Bob "too many too soon" Sears and about a child who died of Hib. If you peruse the comments in those two posts, you will see him once again disparaging science, touting his own personal clinical experience over the science failing to find a link between vaccines and…
SETTING: A NONDESCRIPT CLINIC IN AUSTIN, TEXAS TIME: AFTER DARK It had been a long, hard day at the clinic. The man trudged to the back of the building and plopped himself down on a large, cushy leather office chair, causing it to spin around. He was fiftyish, but still boyish in appearance, possessed of a seemingly unflappable self-confidence. Even so, he was not happy. Damn, I hate being here. He thought. I'd much rather be back in London than stuck in this hick state. At least Austin is about as good as it gets here. I suppose it could be worse; I could be in Arkansas. He sighed. "Damn…
I've warned time and time again what the price will be if the Jenny McCarthy and her fellow arrogantly ignorant band of vaccine "skeptics" continue to get more and more traction. So have many others. It is true that, for the moment, vaccination rates overall remain high in the U.S., but there are numerous troubling signs that the propaganda being spread by Generation Rescue and the anti-vaccine movement is having an effect, with outbreaks of vaccine-preventble diseases popping up in areas with high levels of "philosophical" exemptions. In such areas, vaccination rates can easily fall well…
Yesterday, I wrote a post about what fellow ScienceBlogger Isis would term "hot, hot science." As much as I love science like that, writing such posts is a lot of work and takes considerably longer than my run-of-the-mill bit of insolent brilliance. Often, after writing an analysis of a peer-reviewed paper like that, I need a bit of a break. No, not a break in writing, but a break in difficulty. To that end, I had seen David Kirby's latest bit of disingenuous goalpost shifting over on The Huffington Post, but damn if Steve Novella didn't beat me to it. I had thought of taking sloppy seconds,…
I don't much like Oprah Winfrey. I know, I know, it's a huge surprise to anyone who reads this blog, but there you go. Over the last four years, I've had numerous reasons to be unhappy with her, mainly because, as savvy a media celebrity and businesswoman as she is, she has about as close to no critical thinking skills when it comes to science and medicine as I've ever seen. Arguably there is no single person in the world with more influence pushing woo than Oprah. Indeed, she puts Prince Charles to shame, and Kevin Trudeau's is a mere ant compared to the juggernaught that is Oprah's media…
I'm a bit envious of Dawn Crawford. Why am I envious? She has a badge of honor I have yet to obtain. Jenny McCarthy has blocked her on Twitter. Darn. I'm going to have to see if I can get Jenny to block me too.
Hot on the heels of yesterday's paper in Pediatrics showing that vaccine refusal elevates the risk of pertussis in a child by nearly 23-fold, a commentary in PLoS Biology asks what can be done to combat anti-vaccine misinformation. Entitled A Broken Trust: Lessons from the Vaccine-Autism Wars, it's an interview with a professor of medical anthropology at UCSF named Sharon Kaufman, who took a 26 month hiatus from her usual work on aging and longevity to study the anti-vaccine movement from an anthropological perspective. Her observations in some way echo observations I've been making as a…
One of the claims of the anti-vaccine movement that most irks me is that their actions do not risk harm to anyone other than their own unvaccinated children. Given that vaccination against many infectious diseases also depends on the concept of herd immunity to provide protection to members of the population who either cannot be vaccinated for medical reasons, are too young to be vaccinated, or who belong to the minority who do not develop adequate immunity to vaccination, such claims are patently false. However, another frequently stated belief is that vaccines are ineffective, that they are…
On Thursday and Friday, the Chicago Tribune ran a two part series (part 1 and part 2) about what is arguably one of the worst atrocities (I agree with Steve Novella on this one) committed against autistic children in the name of antivaccine lunacy. Specifically, these articles discussed Mark and David Geier's Lupron protocol, which I blogged about three years ago, and Dr. Mayer Eisenstein, the founder of the woo-friendly Homefirst medical practice in suburban Chicago, whom I've also blogged about in the past. Surprisingly, the reaction from the antivaccine propaganda blog Age of Autism has…
As promised, the Chicago Tribune served up the followup article to its expose of father-and-son autism quacks Mark and David Geier. This time around, the Trib takes on Dr. Mayer Eisenstein of the woo-friendly suburban Chicago medical practice known as Homefirst in two articles, Autism doctor: Troubling record trails doctor treating autism and Dr. Peter Rosi places blame on some parents for their babies' deaths (Dr. Rosi is one of Homefirst's longest-serving doctors). The reason Dr. Eisenstein came to the Trib's attention is because (1) he has started using the Geiers' Lupron protocol and (2)…
I originally joined this wild and woolly collective known as ScienceBlogs back in February 2006. I was not part of the very first wave of bloggers who made up ScienceBlogs when it launched, although I potentially could have, mainly because I had to work out policies about outside employment with my university before I could join up. In any case, one of the very first posts that I did back then that made a bit of a splash was a little ditty I called in my usual inimitable and restrained fashion, Why not just castrate them? It was the dark saga of an even darker father-and-son tag team of…
A reader informs me of a plaintive, heartfelt request from Oprah for help in developing the television show of her new protege Jenny McCarthy: You've seen it all over the news...Jenny McCarthy, one of America's funniest and coolest moms and Harpo is giving her, her own show. Here is where YOU come in. What would you like to see featured on Jenny's show? What would you like for her to talk about? What are you and your friends buzzing about? Any topics you'd like for her to tackle? Are there any questions that you have -- that you would love for her to answer? If so -- we definitely want to…
While I'm on the topic, blog bud has proclaimed that he loves Jenny McCarthy's new blog at the Oprah website, in particular her Poop Stories. Personally, when I first saw Jenny's blog, my first thought was that a question I had always had ever since Jenny McCarthy became the chief propagandist for the antivaccine movement had finally been answered. I now know why that cesspit of anti-vaccine lunacy, The Huffington Post, had never invited Jenny McCarthy to blog. HuffPo may not have standards when it comes to science, but at least it has standards when it comes to writing, and Jenny's…
A loving ode to Jenny McCarthy from her good friends, Measles, Mumps, and Rubella: Genius. That's all I can say.Thank you Brian Thompson, a.k.a. the Amateur Scientist. And to you, Jenny McCarthy, the Measles, Mumps, and Rubella offer their profound thanks for saving them from eradication in the U.S., just as they've offered their thanks to Andrew Wakefield for saving them from eradication in the U.K..Bloggers, you know what to do. Spread this video far and wide. E-mail it to your friends. Even better, e-mail it to antivaccinationists. Let's see if we can make this sucker go viral. (Hey,…