medicine
oracknows | November 17, 2015The other day, I suddenly realized that it's been a long time since I've written about the Polish expat doctor in Houston who treats patients with advanced brain cancer with a concoction that he dubbed antineoplastons (ANPs). I'm referring, of course, to Stanislaw Burzynski who, despite the fact that he has no training in medical oncology, has treated thousands of cancer patients with ANPs beginning back in the late 1970s. Somehow, despite the fact that he's never even come close to showing that ANPs are effective and safe against the cancers for which he uses it, the FDA has, with a brief…
oracknows | November 15, 2015It's no secret that I'm not a big fan of naturopathy. It is, as my good bud Kimball Atwood has said, a prescientific system of medicine rooted in vitalism, the idea that there is a "life energy" and a "healing power of nature." Naturopaths invoke very simplistic concepts to explain the cause of disease, such as "toxins," widespread food allergies, gluten, imbalances in qi (the life force energy), and many other pseudoscientific principles. To give you an idea of the kind of pseudoscientific quackery naturopathy encompasses, consider this: You can't have naturopathy without homeopathy, which…
oracknows | November 13, 2015The question of whether it is worthwhile to debate cranks, quacks, and advocates of pseudoscience has long been a contentious issue in the skeptic community. Those of you who've been reading my posts for a while know that I've always come down on the side that it is not a good idea One thing I've learned in my more than a decade of blogging, both here and at my non-pseudonymous other blog, is that advocates of pseudoscience love public debates. Indeed, whenever you see a skeptic agree to a public debate with an advocate of pseudoscience, it's a damned sure bet that it wasn't the skeptic who…
oracknows | November 11, 2015I've used my current pseudonym since at least the late 1990s, first on Usenet and then on the first incarnation of this blog. Not surprisingly in retrospect (although it surprised me at the time), people who didn't like me began trying back in the 1990s to "unmask" me. It began with Holocaust deniers. No, I'm not trying to Godwin this post; it really did begin with Holocaust deniers because, as longtime readers know, my "gateway drug" to skepticism was refuting the lies and misinformation of Holocaust deniers. So, round about the turn of the millennium, a group of Holocaust deniers managed to…
oracknows | November 10, 2015After nearly 11 years (!) at this blogging thing, I thought I had covered pretty much every medical topic a skeptic and supporter of science-based medicine would be interested in covering. However, if there's one thing I've learned over the years, it's that there's always something I've missed, some hole in my blogging oeuvre that needs to be filled. Perhaps when I've been at this for 20 years I'll have filled them all in. Even if that becomes true sometime in the next nine years, I will likely have only filled in the old gaps, while new ones will have formed. Dealing with pseudoscience is…
oracknows | November 8, 2015David Katz doesn't much like skeptics, particularly those of us who question the value of "integrative medicine." In fairness, I can't say that I much blame him. We have been very critical of his writings and talks over the years to my criticism of his statement advocating a "more fluid concept of evidence" more than once, to my pointing out that his arguments frequently boil down to a false dichotomy of either abandoning science or abandoning patients.
Last week, my friend Jann Bellamy discussed an unfortunate special supplement of the American Journal of Preventative Medicine (AJPM)…
oracknows | November 6, 2015As a surgeon, I find Ben Carson particularly troubling. By pretty most reports, he was a skilled neurosurgeon who practiced for three decades, rising to the chief of neurosurgery at Johns Hopkins. Yet, when he ventures out of the field of neurosurgery—even out of his own medical specialty—he routinely lays down some of the dumbest howlers I've ever heard. For example, he denies evolution, but, even worse, he's been a shill for a dubious supplement company, Mannatech. Worse still, when called out for his relationship with Mannatech in the last Republican debate, Carson lied through his teeth…
oracknows | November 5, 2015I've been at this blogging thing for more than a decade now. Looking back on those years, I find it incredible that I've lasted this long. For one thing, I still marvel that there are apparently thousands of people out there who still like to read my nearly daily musings (or, as George Carlin would call them, brain droppings) after all these years. More importantly, being a public advocate for science is a rough business, as I've documented over the years. Back when I first started out, I was completely pseudonymous and anonymous. I kept my real name relatively secret. It was less than five…
oracknows | November 4, 2015Naturopathy is a cornucopia packed to the brim with virtually every quackery known to humankind, be it homeopathy, much of traditional Chinese medicine, vitamin C for cancer, or basically any other pseudoscientific or prescientific treatment for disease that you can imagine. I feel obligated to start most of my posts about naturopathy with a statement like this not just because it's true but because I want to remind my readers that it's true. I particularly want to remind my readers when I see naturopaths revealing their true quack selves when they think no one's watching, but I want to…
oracknows | November 3, 2015I hadn't planned on writing about this again today. (How many times have I started a post with that phrase? I forget, but a lot. Sadly, developments frequently make me change my plans about blogging.) Here's what made me change my plans It was a pair of Facebook posts on hip-hop and fashion mogul Russell Simmons' Facebook page.
Here's post #1:
And here's post #2:
This, of course, is the news report regurgitating antivaccine talking points broadcast in Atlanta late last week by Ben Swann, an all-purpose conspiracy theorist and, apparently, now antivaccinationist, who is anchor for the…
oracknows | October 30, 2015When I wrote about YouYou Tu, the Chinese scientist who won the Nobel Prize in Physiology or Medicine for her successful identification, isolation, purification, and validation of Artemisinin, an antimalarial medication that was quite effective. It was also derived from an herbal remedy used in traditional Chinese medicine (TCM), which has led a fair number of TCM advocates to portray this Nobel Prize as a "validation" or "vindication" of TCM. It wasn't. Nor was it a validation of naturopathy or herbalism, as has been claimed. It was a validation of the good, old-fashioned science-based…
oracknows | October 29, 2015Unfortunately, this happens to be a day when I didn't really have much time to blog, as I had to go to an evening meeting last night related to my work. Fortunately, this corresponds with a most excellent day, a first in my life. Basically, I'm coauthor on a Perspective article published in today's New England Journal of Medicine on trends in metastatic disease in breast cancer and prostate cancer. Even better, it's not behind a paywall (at least for now); so you—yes, you!—can read it. It's also written at a level that I think a lot of our readers will enjoy it, although the strict word…
oracknows | October 28, 2015No doubt, regular readers are probably somewhat surprised that I didn't discuss the antivaccine rally scheduled to be held in Atlanta last weekend that I wrote about last week. As you might recall, this rally consisted of two crappy tastes that taste crappy together, namely Robert F. Kennedy, Jr. and the antivaccine movement together with the Nation of Islam. Given that the Nation of Islam, besides being a truly crank religion on its own, of late has gotten very cozy with the Church of Scientology, thus amplifying the crank factor by orders of magnitude (at least).
Readers not familiar with…
oracknows | October 27, 2015I'm a clinician, but I'm actually also a translational scientist. It's not uncommon for those of us in medicine involved in some combination of basic and clinical research to argue about exactly what that means. The idea is translational science is supposed to be the process of "translating" basic science discoveries into the laboratory into medicine, be it in the form of drugs, treatments, surgical procedures, laboratory tests, diagnostic tests, or anything else that physicians use to diagnose and treat human disease. Trying to straddle the two worlds, to turn discoveries in basic science…
oracknows | October 26, 2015I like to point out from time to time that arguably the most striking difference between science-based medicine (and the evidence-based medicine from which we distinguish it) and alternative medicine, "complementary and alternative medicine" (CAM), or (as it's called now) "integrative medicine" is a concerted effort to change practice for the better based on science and evidence. In other words, in SBM, we are continually doing studies to improve practice. These studies take on two general forms: Comparing new treatments with old to determine if the new treatments work better and, as has…
oracknows | October 23, 2015I consider posts like the one I'm writing now to be public service, an obligation. There are times when I don't want to do them, when they become so sadly, depressingly repetitive in overall outline (and, unfortunately, likely outcome) that it takes an effort to begin. However, given that October is Breast Cancer Awareness Month and as a result these sorts of stories seem to pop out of the woodwork this time of year, I feel I must. It doesn't matter that I just discussed another one of these cases a mere month ago. This time around, the article appears (as is so frequently the case) in The…
oracknows | October 22, 2015I was measured, science-based, and reasonable in yesterday's post about the new American Cancer Society guidelines for screening mammography (which is obviously why that post garnered so few comments, thus teaching me my lesson yet again0, but regular readers know that I can be quite obnoxious and sarcastic and there's a reason why this blog is called Respectful Insolence. It's based on a quote from a character (a computer, actually) in a 35 year old British science fiction series. That character, Orac, is my namesake, and the adopted quote is, "A statement of fact cannot be insolent."
Of…
oracknows | October 21, 2015One of the things that feels the weirdest about having done the same job, having been in the same specialty, for a longer and longer time is that you frequently feel, as the late, great Yogi Berra would have put it, déjà vu all over again. This is particularly true in science and medicine, where the same issues come up again and again and again, often with the same arguments on either side. Sometimes the same players are even involved. So it is with mammography recommendations. Indeed, I'm feeling déjà vu all over again right now, as I read headlines like Women advised to get mammograms later…
oracknows | October 20, 2015If there's one thing that's amusing about the antivaccine movement, it's the disconnect between its members' perception of their own importance and the reality of it, which is that they tend to be a pretty pathetic, risible band. They post their blogs, full of the rage of Dunning-Kruger, thinking that they are putting forth the most sophisticated scientific arguments that real scientists, who have spent their entire professional life studying vaccines and autism, somehow missed and finding evidence of a link that no other scientist can. Of course, pesky things like rigorous study design tend…
oracknows | October 19, 2015Two of the great "icons"—if you can call them "great" given that they're icons but hardly "great"—of the antivaccine movement are Andrew Wakefield and Jenny McCarthy. Over the last decade, they have arguably been the most influential people in the antivaccine movement. The reasons are simple. Let's look at Jenny McCarthy first. In 2007, when her child Evan was diagnosed with autism and she blamed MMR vaccine for it, McCarthy became virtually overnight the single most famous celebrity antivaccine advocate. With her then-boyfriend Jim Carrey, in 2008 she led an antivaccine march on Washington…