complementary and alternative medicine
oracknows | October 9, 2008Well that didn't take long, did it?
Three days ago, I described a study that I had noticed in the October 1 issue of Cancer Research that described an animal study that strongly suggested that vitamin C administered at sufficiently high doses may interfere with the action of multiple chemotherapeutic agents. You can read the link for full details of the study as discussed by yours truly. In fact, although I only blog sporadically about the exaggerated claims of advocates of vitamin C as a cancer cure, but when I do I like to think I hit the mark, starting two and a half years ago when I wrote…
oracknows | October 8, 2008Here we go again.
It seems just yesterday that I was casting a skeptical eye on yet another dubious acupuncture study. OK, it wasn't just yesterday, but it was less than two weeks ago when I discussed why a study that purported to show that acupuncture worked as well as drug therapy for hot flashes due to breast cancer therapy-induced menopause. Unfortunately, these days these sorts of dubious studies seem to be popping up fast and furious like Whac-A-Mole, so much so that I can't always keep up with them. So it is again, although this time it's acupressure, not acupuncture. Unfortunately,…
oracknows | October 7, 2008...it'll be because the flu vaccine poisoned me, of course!
That's right. Today I got my flu shot, complete with thimerosal and formaldehyde! I do put my money where my mouth is, so to speak. No word on whether there was any of the dreaded Polysorbate 80 in the vaccine, though. Oh, well. Maybe next time.
Also, while we're at it, my latest post over at The ScienceBlogs Book Club is up and ready for your perusal. Read it, enjoy it, trash it if you like. Just don't ignore it.
You know how much I hate it when my posts are ignored.
oracknows | October 7, 2008For women undergoing menopause, hot flashes are a real problem. In my specialty, as I've pointed out before, women undergoing treatment for breast cancer are often forced into premature menopause by the treatments to which we subject them. It can be chemotherapy, although far more often it's the estrogen-blocking drugs that we use to treat breast cancers that have the estrogen receptor. Estrogen stimulates such tumors to grow, and blocking estrogen is a very effective treatment for them, be it with tamoxifen or the newer aromatase inhibors like Arimidex. The utterly predictable consequence,…
oracknows | October 6, 2008Sometimes I have to look for blog ideas, trolling through various alternative medicine sites, medical news sites, or science news feeds or my medical and science journals. Sometimes ideas fall on me seemingly out of the blue. This is one of the latter situations. This time around, as I do twice a month I was perusing the very latest issue of Cancer Research, hot off the presses October 1. As I did so, it didn't take me long to come across an article from the Memorial-Sloan Kettering Cancer Center and the Herbert Irving Comprehensive Cancer Center at Columbia entitled Vitamin C Antagonizes the…
oracknows | October 6, 2008As you may remember, the evening after the Hollywood face of the antivaccine P.R. machine Jenny McCarthy was scheduled to take part in a web chat. At the time, I suggested sending questions in to the Oprah website, to see if any would get through. I'm sure there was some serious screening and vetting of possible questions; so I suggested trying to word them in such a way as to indicate Jenny's ignorance without triggering the censors. Apparently never was heard a discouraging word in the web chat (big surprise there), but apparently one rather clever wag did manage to get a question through…
oracknows | October 4, 2008Unfortunately, I'm going to be ensconced in my Sanctum Sanctorum most of the day, pounding out text far less fun than the text I like to pound out for Respectful Insolence. However, I have to admit that this video sums up the attitude behind a whole lot of woo that I like to apply a skeptical deconstruction to--with music!
oracknows | October 3, 2008...at The ScienceBlogs Book Club has been posted. Go forth and enjoy. As always for these Book Club Posts, no comments are allowed here. Got a response? Hate my guts? Think I'm in the pocket of Big Pharma, Big Government, and the Illuminati, too? At least for this post, say it over there!
oracknows | October 1, 2008I guess that since my resistance failed, and I couldn't resist posting yesterday about the burning stupid that is Jenny McCarthy and her arrogance of ignorance in claiming that vaccines caused her son's autism and her campaigning to "Green Our Vaccines" (in reality, a smokescreen to hide her antivaccinationism), I thought why not go whole hog and get it out of my system? Let's just take in a concentrated dose, as the more Jenny talks the more she discredits the antivaccine movement among anyone with a lick of scientific literacy:
Embedded video from CNN Video
Jenny's on fire with stupid!…
oracknows | October 1, 2008...has been posted over at The ScienceBlogs Book Club.
Head on over. As will be the case for all my posts at the Book Club, please leave comments there, not here. Thanks.
oracknows | October 1, 2008Readers may be wondering why I haven't written about Jenny McCarthy's latest brain dead outburst against Amanda Peet. (Actually, brain dead is too kind a description of it, given that Jenny's retort in essence boils down to her having an "angry mob" on her side making Amanda "completely wrong.") It's because I decided to try to resist for once in my life. And I was doing really good at it, too, even though several readers sent me links to various stories about Jenny McCarthy's outburst. Still, I resisted. Even after antivaccinationist financier J. B. Handley wrote a post demanding of Amanda…
oracknows | October 1, 2008Just a quick announcement here:
The ScienceBlogs Book Club is back up and running, and this time the book under discussion is the latest by that Dark Lord of Vaccination himself, that Darth Vader to the antivaccinationist Luke Skywalker, otherwise known as Satan Incarnate to Jenny McCarthy, J.B. Handley, Andrew Wakefield, Dan Olmsted, and the crew of antivaccinationists spreading misinformation and endangering public health and promoting an amazing panoply of quackery to "cure" autism, Dr. Paul Offit. The book under discussion is Autism's False Prophets: Bad Science, Risky Medicine, and the…
oracknows | October 1, 2008When I first started blogging, I liked to refer to myself as a booster of evidence-based medicine (EBM). These days, I'm not nearly as likely to refer to myself this way. It's not because I've become a woo-meister of course. Even a cursory reading of this blog would show that that is most definitely not the case.
So what's changed? Basically, I've come to the realization that EBM is an imperfect tool. Don't get me wrong, EBM goes a long way towards systematizing how we approach clinical data, but there's one huge flaw in it. (I can just see a quack somewhere quote-mining that sentence: "Orac…
oracknows | September 30, 2008Yesterday's post was a result of the feeling that I had been getting too snarky for too long a time without doing some serious science or medical blogging. Not that there's anything wrong with being snarky, but a continuous diet of snark eventually gets dull--and not just to readers. However, science blogging is hard. Posts like that take a lot of work (which is why I have a propensity to write such posts over the weekend and post them on Monday). After I do a serious, thoughtful post like that, sometimes I just need a diversion. Sometimes I need to examine something that allows me to deliver…
oracknows | September 29, 2008More than two-thirds of breast cancers make the estrogen receptor. What that means is that these tumors have the protein receptor that binds estrogen, which then activates the receptor and causes all the genes that are turned on or off by estrogen to be turned on and off. That's how estrogen acts on normal breast epithelial cells and on breast cancer cells. The significance of this observation is that estrogen receptor-positive (ER+) breast cancers respond to estrogen. Indeed, estrogen contributes to their growth, and blocking estrogen is an effective treatment against them. Indeed, that most…
oracknows | September 24, 2008Here we go again.
Tuesday night and yesterday, you probably saw it, plastered all over the media, in the newspapers, on ABC, on the radio, in press releases, and around the blogosphere. Yes, it was another bit of science by press release, with news outlets practically falling all over themselves to hype the results of an acupuncture study reported earlier this week at the annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO). Leading the pack was ABC News:
A new medical study finds that acupuncture, an ancient form of healing that has been around for thousands…
oracknows | September 23, 2008Thanks to our "friends" at the Age of Autism, I've learned something interesting.
I knew that antivaccinationist "mother warrior" and Indigo Child Supreme Jenny McCarthy was slated to appear tomorrow, September 24, on the television show that arguably serves as the most powerful and pervasive promoter of woo, magical thinking, and dubious health advice in the world, The Oprah Winfrey Show. I hadn't actually planned on watching it (I'm never home when it's on anyway), and setting the DVR to record it for later viewing seems more than I'm willing to do to expose my brain to the neuron-…
oracknows | September 22, 2008Every blogger encounters a post that he wishe he or she had written. Here's one such time, as Prometheus schools us on how alternative practitioners manage to be so persuasive and convincing:
How they do the voodoo that they do so well - Part 1
How they do the voodoo that they do so well - Part 2
oracknows | September 22, 2008Oddly enough, I'm more tired this morning than I was on Friday.
That's the sort of thing that happens when I actually do as much work over the weekend as I often do on two typical weekdays. The reason is that I've suddenly found myself with an unexpected promotion, and--oh, by the way--there's stuff that needs to be done on Monday. Consequently, my originally intended topic for Monday will have to wait until Tuesday or Wednesday, mainly because it might require a bit of thought. That's OK. It'll wait. Besides, it'll be much more useful and educational if I have a little time to think about it…
oracknows | September 19, 2008As a cancer surgeon, I maintain a particularly intense contempt for peddlers of cancer quackery. Although I've been fortunate enough not to have had to see the end results of it more than a handful of times in my career, women with bleeding, stinking, fungating tumors with widespread metastases that could have been treated if they hadn't decided upon woo rather than good old-fashioned surgery, radiation, and chemotherapy, I've become aware of enough such cases and seen the dishonest marketing of quackery enough to drive me to maintain this blog and undertake other activities to promote…