Palladia/Toceranib (Dog cancer drugs)

A few months ago, a tyrosine kinase inhibitor anticancer drug for people, this month, one for dogs.

i-de9259e1defc0dd864169bf8a23fc78f-palladia.png

It is made to treat cutaneous mast cell tumors, which apparently account for about a quarter of dog cancers.

I know a lot of people drugs end up in pets, but do pet drugs ever end up crossing over into human medicine? Anyone know anything about how the decision to go after a dog-specific drug works? Just cheaper to go after?

Tags

More like this

Look, scientists are nuts.  Virologists, on the other hand, are certifiably insane.  As Hedwig would say, virologists make the strangest things seem suddenly routine.  Yesterdays absurd future technology (GENE THERAPY!) is now something as miraculous as curing genetic diseases, and as mundane as an…
tags: cancer, smokers, pets Maybe this will surprise you but, having worked in cancer research for a few years, it isn't surprising to me to learn that secondhand smoke can cause cancer in your pets as well as in people. I mean, this just makes sense, ya know? However, according to a study study…
No. But the WSJ would like you to believe so. One libertarian talking point I hear a lot (Cato of course loves this story), and is repeatedly pushed by the WSJ, is that the market and consumers should decide the safety and efficacy of drugs - not dirty gov'mint bureaucrats who want nothing but…
In a good post about puppy mills, Amanda Marcotte made a good point about domesticated versus undomesticated pets (italics mine): This would probably mean that people couldn't get exotic pets, and that isn't really the sort of thing that would keep me up at night, either. I understand the urge to…

There was a dog obesity drug that was created recently that failed when tested with humans but had passed animal tests with dogs first.
You are right that they probably would not try to create a cancer drug just for dogs.

Since all human drugs are first tested in animals and only the ones effective there make it through, you could say that all human drugs are also "pet" drugs (if you consider rats, rabbits and monkeys as potential pets)

I worked for a time in a pet store. A woman came in and bought all of our fish treatment drugs, including anti-fungals and anti-biotics. When I asked her why she was buying our entire stock, she told me these were going to be sent to another country where they have not any medical system. She said people were desperate for drugs to treat all manner of conditions. It shocked me at the time, now it just makes me sad

I know one case, the Ivermectin, It was a broad-spectrum antiparasitic agent just for animals, but actually its activity against nematodes in humans is weighty.