Biotin (Different things to different people)

Biotin is just a vitamin to most of us. To a lot of biologists, though, it plays the unlikely role of some of the strongest glue around.

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There are proteins known as avidins that bind biotin so strongly that it's pretty much irreversible. If you stick biotin on something you're interested in, and stick avidin on a solid surface, you've pretty much got a molecular glue that's not going anywhere.

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Biotin and the like will also promote the benzoin condensation when the Nanny State whacks your pee-pee for potential hazards. Let's all be too girly to use cyanide like real men.

Will it case-harden steel? I think not.

Actually, it can be used to case harden steel, historicly, collogeneous materials were used as a carbon source through most of the iron age, all you need is carbon rich, not too volatile material to coat the steel. Bone glue was prefered though.

I am always amazed at how ubiquitous biotin is in biochemical studies. I should really look up a crystal structure of biotin-avidin.

Biotin deficiency - a good reason to avoid raw egg white.

You forgot its most important use: It transfers CO2 molecules in biological systems!

By Ryan Sullivan (not verified) on 05 Mar 2008 #permalink

Yes, I agree with Ryan, as biotin plays an important role in the fatty acid biosynthesis of bacteria.

By Kevin Kuan (not verified) on 10 Mar 2008 #permalink