Benzoylecgonine (Sewer tattletale)

Benzoylecgonine is the primary metabolite of cocaine - it's actually just cocaine minus a methyl group. It's not really used as an intoxicant, but it does have one interesting use: figuring out just how much cocaine people are using.

One study in 2005 in Germany examined the total amount of benzoylecgonine in wastewater (a good chunk of cocaine-derived benzoylecgonine is excreted in urine). Their result suggested the proportion of cocaine users was substantially larger than the 8 per 1,000 previously thought.

i-927c5559733e08c28064672fd150e7f8-benzoylecgonine.gif

Tags

More like this

Floyd Landis, most recent winner of the Tour de France, has tested positive for testosterone use: Landis denied cheating and said he has no idea what may have caused his positive test for high testosterone following the Tour's 17th stage, where he made his comeback charge last week. But he aims to…
Last week's Casual Friday study was all about money. The basic question was simply what it means to be rich -- how much income and net worth does it take before you consider someone to be wealthy? We received over 1,000 responses. Perhaps our most interesting finding was simply the diversity of…
It’s only natural that during a crisis we look to single, “silver bullet” technical solutions, after all, they are supposed to be effective against werewolves, witches, and other monsters. For monsters like the ongoing severe California drought, the current favorite silver bullet is seawater…
As I mentioned earlier, there's a really interesting paper on mammal evolution in the latest issue of the journal Nature. The authors of the paper compiled a really fantastic sampling of molecular data that included data from about 99% of all currently known extant mammals. The data was then used…

In the hexagon which contains the Nitrogen atom, there are three bonds (obviously, that's how it appears on the drawing). What are those exactly?

The six-membered ring subsystem (the hexagon) would be called "piperidine" if it were on its own. Since it's fused into another ring system (because of the five-membered nitrogen containing ring formed by those other two carbons) and the nitrogen has an extra methyl, it is a bigger ring system called tropane.

The three bonds coming from the nitrogen atom are all going to carbon atoms. Every vertex in one of these line drawings is a carbon atom - unless the carbon has multiple bonds (multiple lines) or a charge, it forms four bonds. The same is true for "N" being nitrogen, except it forms three when uncharged and only participating in single bonds. Every carbon has hydrogen atoms making up its remaining substituents. The two carbons bound to the nitrogen that are part of the ring, therefore, are -CH2-, or "methylenes", and the carbon bound only to nitrogen is -CH3, or a "methyl".

Hope that makes sense (and I didn't answer a question you weren't asking, I was a little unclear on what you meant!)

Alright Uncle Al, I don't know if you just haven't managed to find the right side of the bed to wake up on yet or not, but your comments generally seem to have about 100% more snarkiness than is actually required to explain chemistry. God forbid that someone who isn't that well acquainted with the subject express some interest in it.

Ah ok. Thanks MotD. And Jon, Uncle Al's comment is just ok too. I don't really care what he thinks. Wouldn't have posted the question if I did anyway.

if some was hair tested 3 months ago and this drug and cocaine showed up in there hair and you had been using hard for the last 2 years then they did another hair test in less then 3 months and it still shows up and your hair is long but you haven't used in 3 months how can this be confrimed since it is still showing up positive

Is there another substance[s] that would mimic benzoylecgonine in the urine or possibly produce a false positive?

By jamie----corpu… (not verified) on 20 Sep 2007 #permalink

How long does benzoylecgonine stay in the liver. Long time since cocaine use. Can any other subtance be at blame??

Is there another substance[s] that would mimic benzoylecgonine in the urine or possibly produce a false positive?

By joshua bess (not verified) on 06 Mar 2009 #permalink

when was Benzoylecgonine discovered?