naked mole rat
A new article published in Physiological Reviews compared some remarkable similarities and differences between naked mole rats and humans. Both are relatively long-lived, highly social and have low natural selection pressures. But, this is about all they have in common. While humans are prone to developing age-related cancer, diabetes, heart disease and dementias, naked mole rats are rather resistant to these diseases. Instead, naked mole rats appear to maintain a youthful state throughout their long lives of 30+ years, compared to a mere 3 years for a mouse. To top it off, they do not…
Image of a naked mole rat By Roman Klementschitz, Wien - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=252701
Researchers trying to find cures for cancer find naked mole rats rather interesting. Not only are these animals long-lived by rodent standards, they are also resistant to the development of cancer. By long-lived, we are talking up to 30 years! A team of researchers from Hokkaido University and Keio University in Japan have now isolated stem cells from the skin of naked mole rats and induced them to revert back to pluripotent stem cells, the type capable of…
Image of a naked mole rat from www.animals.sandiegozoo.org
The naked mole rat is the longest lived rodent species (>31 years). Unlike most mammals, they seem resistant to many age-associated ailments until much later in life, making them an exciting model of healthy aging. They are also resistant to the development of cancer as mentioned in this prior post.
According to the CDC, cardiovascular disease is currently the leading cause of death in the United States, claiming the lives of roughly 600,000 people annually (or 1 out of every 4 deaths). In a new study published in the American…