Colorado

Someone yesterday was not very happy with my attitude towards naturopaths, as evidenced in my post yesterday about the death of a young woman named Jade Erick due to intravenous infusion of curcumin by—you guessed it—a naturopath. Amusingly, that someone going by the 'nym of JR said that he or she didn't "like the tone of this article and it’s complete disregard for naturopaths." Well, JR, you're right. I do have a complete disregard for naturopaths because they are quacks who mix a small amount of good advice about diet and exercise with a whole lot of pure quackery (like homeopathy) and…
The Pump Handle is on a holiday break. The following, which was originally published on Feb. 29, is one of our favorite posts from 2016. by Liz Borkowski, MPH I've written before about the Colorado Family Planning Initiative, which in 2009 started providing free IUDs and contraceptive implants (the two forms of long-acting reversible contraception, or LARC) to low-income women at family planning clinics in 37 Colorado counties. Between 2008 and 2014, the state's teen birth and abortion rates both dropped by 48% (see this webinar for details). While teen birth rates have been declining…
Although the US still has a long way to go in preventing unintended pregnancies, an article published earlier this month in the New England Journal of Medicine had some good news:  The proportion of US pregnancies that were unintended dropped from 51% in 2008 to 45% in 2011. Lawrence B. Finer and Mia R. Zolna of the Guttmacher institute analyzed data on pregnancy intention from the National Survey of Family Growth, and note that the rate of unintended pregnancy declined for every income and education group and all racial and ethnic groups. Disparities still persist -- rates are still highest…
I've written before about the Colorado Family Planning Initiative, which in 2009 started providing free IUDs and contraceptive implants (the two forms of long-acting reversible contraception, or LARC) to low-income women at family planning clinics in 37 Colorado counties. Between 2008 and 2014, the state's teen birth and abortion rates both dropped by 48% (see this webinar for details). While teen birth rates have been declining nationwide in recent years, Colorado's decline was the largest. LARC methods have become increasingly popular in the US over the past several years. This is likely…
Last week, Vox’s German Lopez highlighted a recent study that demonstrates how improving access to the most effective contraceptives can slash the rates of unintended pregnancies and abortions among teens. After the Colorado Family Planning Initiative (CFPI) started providing free IUDs and implants to low-income women at family planning clinics, the teen birth rate and abortion rate dropped sharply. Lopez notes that the teen birth rate has been declining nationwide, but Colorado’s has dropped more quickly: “Between 2008 and 2012, the state went from the 29th lowest teen birth rate in the…
One of the biggest medical conspiracy theories for a long time has been that there exist out there all sorts of fantastic cures for cancer and other deadly diseases but you can’t have them because (1) “they” don’t want you to know about them (as I like to call it, the Kevin Trudeau approach) and/or (2) the evil jackbooted thugs of the FDA are so close-minded and blinded by science that they crush any attempt to market such drugs and, under the most charitable assessment under this myth, dramatically slow down the approval of such cures. The first version usually involves “natural” cures or…
There are times when supporting science-based health policy and opposing health policies that sound compassionate but are not are easily portrayed as though I’m opposing mom, apple pie, and the American flag. One such type of misguided policy that I’ve opposed is a category of bills that have been finding their way into state legislatures lately known as “right to try” bills. Jann Bellamy over at SBM and I have both written about them before. With the passage of the first such bill into law in Colorado in May, followed by Missouri and Louisiana, and its heading to the voters of Arizona as…
With Matthew Heberger. This is a version of a post from the blog "Pacific Institute Insights" How much water is there in America’s rivers, and where is it? Perhaps unsurprisingly, people have little sense of how their local water resources compare in size to other water resources. “Is that a big river? A little river?” One of us [Gleick] grew up along the Hudson River on the East Coast, and encountered rivers that seemed to be about the same size: the Susquehanna, the Delaware, the Potomac. Anyone living in the West working on water issues becomes more familiar with the Colorado, the…
High temperatures and dry conditions have caused the outbreak, increased intensity, and rapid spread of numerous wildfires in Colorado. Again. Fires happen, but the number, size, and intensity of wildfires in the western United States has been very high in recent years, and this is caused by global warming. Global warming causes more rain and more frequent and more severe storm lines. More rain causes more plant growth in otherwise arid regions, and severe storms knock a lot of that vegetation down. This causes more light to get to the ground, so "ladder" vegetation, which enhances fire…
It's just one more cut on the road to the proverbial death by a thousand cuts. I'm referring, unfortunately, to last week's development in the state of Colorado. Specifically, I'm referring to the Colorado legislature's truly boneheaded decision to license naturopaths, thus giving the imprimatur of the state to quackery and, in essence, legalizing a whole lot of that quackery. It's been a long time coming, and, say what you will about Colorado naturopaths, they're persistent and disciplined. As a result, after years of effort, they finally got what they wanted, although apparently not all…
The Colorado River, recently named America’s most endangered river, supports millions of people in the American Southwest and northwest Mexico and helps irrigate millions of acres of land. It is shared by seven states in the U.S. and Mexico, through a complex series of legal agreements and treaties. Yet every drop of water on the river is accounted for, used, reused, and transpired away, and today, no water reaches the Colorado River delta in an average year. Quite simply, demands on the river exceed the river’s average supply, and this problem is projected to get worse as populations…
On the heels of the recruitment of Deborah Blum to ScienceBlogs, I am happy to welcome journalist Maryn McKenna to our neck of the ether. Her inaugural post can be read here. McKenna's blog is called Superbug, reflecting the title of her most recent book, SUPERBUG: The Fatal Menace of MRSA, and her general interests in infectious diseases and food safety. Her 2004 book, BEATING BACK THE DEVIL: On The Front Lines with the Disease Detectives of the Epidemic Intelligence Service (of the US Centers for Disease Control and Prevention), named among Top Science Books of 2004 by Amazon.com and an "…
Last Monday marked 17 years since Eric Young led off the first Colorado Rockies baseball game with a home run that triggered a collective, mile-high orgasm for the 80,227 spectators gathered in the old Denver football stadium. The advent of the expansion Rockies also launched a Pharmboy laboratory birthday celebration week tradition marked by two days off: one for a lab ski day in the high country followed later in the week with a Rockies game and the finest handcrafted ale offered by Denver's Wynkoop Brewery. I was reminded of this by my Twitter buddy, Mike Smith (@M1k303) who taunted me a…
This post is the third in a series on the origin and history of HeLa S3 cells. The first post details how I came about to ask this question when launching my independent research laboratory. The second post details the life and careers of the legendary physician-scientist pioneer, Dr. Florence Rena Sabin. Today, we take up a discussion where we will finally learn the origin of HeLa S3 cells, complete with original literature citations. A recap We left our previous discussion with the final and still-productive years of Dr. Florence Rena Sabin. After graduating from Johns Hopkins Medical…
This post is the second in a series on the origin and history of HeLa S3 cells. The first post can be found here. In this post, we discuss the life and careers (yes, careers) of the remarkable physician-scientist, Florence Rena Sabin. "Too bad you're not a boy, you would have made a good doctor." Florence Rena Sabin was born in the mining town of Central City, Colorado, on November 9, 1871, two years after her sister and lifelong companion, Mary. Florence's father. George Sabin, had moved from Vermont to Colorado in the midst of the Colorado gold rush and a notable 1859 gold strike between…
When I first started my independent academic laboratory in 1992, it was in a brand new facility across the parking lot from a then 40-year-old building named in honor of the woman to the right. I took on a big teaching load from day one and while I had some cash left from the $50,000 start-up package, I didn't hire a technician immediately. So it fell upon me to do all the ordering of the basic supplies to get the operation rolling. No problem, right? I ordered much of my own stuff as a postdoc so it should be no problem to get everything I need to start the lab from scratch. One of the…
Update: New ScienceBlogs colleague, Sharon Astyk at Casaubon's Book, brought my attention to the fact that this local southern Colorado story has been picked up by CNN. Although I originally wrote this post rather tongue-in-cheek, some scientific evidence has accumulated for the benefits of cannabis in neuropathic pain, cancer pain and nausea, as well as muscle spasticity in multiple sclerosis. For what appears to be a subset of individuals, marijuana is superior to prescription drugs in terms of efficacy and side effect profile. Equivocal results with a standardized cannabis extract…
In an article by Wayne Heilman of the Colorado Springs Gazette, I learned of a US FDA action against contract drug manufacturer Provident Pharmaceuticals. The company has been cited for good manufacturing practices (GMP) violations as well as the manufacture of unapproved drugs. The GMP violations are of a magnitude that FDA requested that Provident hire a GMP training consultant to bring the facility up to snuff. However, Heilman seized upon an interesting side light in the warning: the names of the unapproved drugs apparently made by the company are missing from the detailed warning letter…
The region of southern Colorado on either side of the Sangre de Cristo Mountains is quite special to the Pharmboy family. The high plains to the east and San Luis Valley to the west are sparsely populated, stunningly beautiful with a veritable mine of geological treasures, and are unlikely to be built up in the PharmKid's lifetime. In fact, most counties down there have fewer people now than they did in 1900. It is also rugged and you can easily die out there. Which gets you in touch with what matters. Bighorn sheep and West Spanish Peak outside of La Veta, Colorado, about 60 miles east…
Twenty years ago this morning, I had to defend a body of work that contained this paragraph on page 24: HeLa cells are a human cervical carcinoma cell line having a doubling time of 24 hr and were obtained from Dr. Bert Flanegan, Dept. of Immunology and Microbiology, University of Florida. HeLa cells were maintained as subconfluent monolayer cultures in minimal essential media (alpha modification; GIBCO) with 10% fetal bovine serum (GIBCO) at 37° under a humidified atmosphere containing 5% CO2. Cells were maintained in logarithmic growth by subculturing every other day using 0.05% trypsin/0.…