CJD

Student guest post by Bradley Christensen No, this isn’t a clip from a science fiction movie.  Although dramatic, this does occur in the brains of some people and animals around on our home planet.  What is a prion you ask?  Prions are almost as mysterious to the scientists that research them as they are to me, you and the neighbor down the street.  Prion is a term used to describe an abnormal and particularly destructive strand of protein found in the brain.  Proteins are the building blocks of the muscles and tissues of our bodies that work combine together to perform different functions. …

Mark Pendergrast writes: To kick off this book club discussion of Inside the Outbreaks, I thought I would explain briefly how I came to write the book and then suggest some possible topics for discussion. The origin of the book goes back to an email I got in 2004 from my old high school and college friend, Andy Vernon, who wrote that I should consider writing the history of the EIS. I emailed back to say that I was honored, but what was the EIS? I had never heard of it. I knew Andy worked on tuberculosis at the CDC, but I didn't know that he had been a state-based EIS officer from 1978…

Alzheimer's disease is the most common form of dementia in the world, affecting more than 26 million people. Creutzfeld-Jacob disease (CJD), another affliction is far less common, but both conditions share many of the same qualities. They are fatal within a few years of diagnosis, they are incurable and they involved the crippling degeneration of the brain's neurons. Now, a group of Yale researchers have discovered that the two diseases are also linked by a pair of critical proteins. Look into the brain of someone with Alzheimer's disease and you will see large, insoluble "plaques" sitting…

tags: Bovine spongiform encephalopathy, BSE, mad cow disease, Creutzfeldt-Jakob Disease, CJD, pathogenic mutation, prion protein gene Image: Orphaned. Mad Cow Disease, technically known as Bovine Spongiform Encephalopathy (BSE), is one of a group of transmissible diseases that destroy brain tissue, collectively known as Transmissible Spongiform Encephalopathies (TSEs). TSEs are an unknown agent(s) that act by damaging the structure of brain proteins known as "prions" (PREE ons). In turn, these damaged prion proteins damage other normal prions and together, they build up to collectively…