birth defects

Last year’s emergency Zika funding is about to run out and there’s no new money in the pipeline. It’s emblematic of the kind of short-term, reactive policymaking that public health officials have been warning us about for years. Now, as we head into summer, public health again faces a dangerous, highly complex threat along with an enormous funding gap. “The Zika threat will get worse,” said Claude Jacob, chief public health officer at the Cambridge Public Health Department in Massachusetts and president of the National Association of County & City Health Officials (NACCHO). “And the…
In a new study — the first of its kind — researchers fed water laced with fracking chemicals to pregnant mice and then examined their female offspring for signs of impaired fertility. They found negative effects at both high and low chemical concentrations, which raises red flags for human health as well. “These are preliminary findings,” Susan Nagel, the study’s senior author and an associate professor in Obstetrics, Gynecology and Women’s Health at the University of Missouri School of Medicine, told me. “But I think they suggest that we should absolutely be looking more closely at the…
Scientists working to understand the implications of Zika's new prevalence in the Americas have found strong evidence that infection with the virus can cause fetal abnormalities and even miscarriage in pregnant women. On The Pump Handle, Liz Borkowski examines a series of studies conducted on Zika, including one which found the virus infected "most of the cortical neuron progenitors, which form the brain’s cortex" more quickly than other types of stem cell. This may be how the virus causes microcephaly, a birth defect resulting from abnormal brain development in the womb. On Discovering…
Do environmental factors such as toxins contribute to autism? On Respectful Insolence, Orac looks at a new study which found a correlation between birth defects and the eventual development of autism. Orac says this correlation has already been demonstrated, along with "autism and exposure to teratogens, specifically at least maternal rubella infection, thalidomide, valproic acid, and misoprostol." But could other chemicals be influencing higher rates of birth defects and autism in certain areas? Many people believe that autism-inducing toxins are found in vaccines. But autism's correlation…
Does your face reveal what’s in your heart? It might – even more than you know. Take, for instance, a common group of birth defects – forms of a disorder called DiGeorge syndrome. Around one in 4000 is born with this syndrome, which arises from a deletion of a short segment of chromosome 22.  Among other problems, this deletion nearly always involves deformations in both the face and the heart. Sculpture: Igor Mitoraj The Institute’s Prof. Eldad Tzahor had already shown that face and heart go together: Very early on in the developing embryo,  the progenitor cells that will become heart…
In just eight years, the incidence of congenital birth defects in Iraq's Al Basrah Maternity Hospital increased 17-fold, a new study reports. An earlier study found the incidence of birth defects at that hospital to be 1.37 per 1,000 live births between October 1994 and 1995 (out of more than 10,000 births total); in 2003, the rate had jumped to 23 per 1,000 live births. The authors also report that, in an analysis of hair samples from 44 Fallujah children with birth defects -- the most common being congenital heart, neural tube, and facial clefting defects -- and 10 Fallujah children without…
Mark Pendergrast writes: To kick off this book club discussion of Inside the Outbreaks, I thought I would explain briefly how I came to write the book and then suggest some possible topics for discussion. The origin of the book goes back to an email I got in 2004 from my old high school and college friend, Andy Vernon, who wrote that I should consider writing the history of the EIS. I emailed back to say that I was honored, but what was the EIS? I had never heard of it. I knew Andy worked on tuberculosis at the CDC, but I didn't know that he had been a state-based EIS officer from 1978…
This seems to have become unofficial volcano week, here at ScienceBlogs. If you haven't been following the coverage of the Eyjafjallajökull eruption at Erik Klemetti's Eruptions blog, you should consider doing so. Also, Dr. Isis has a post on how the eruption has fouled up all nuclear imaging plans at her place of research, and Ethan explains how volcanic lightening works. Our benevolent overlords have further commented: "Eyjafjallajökull's ill temper has been an unexpected object lesson in the complexity and interconnectedness of our environment, technology, and social networks." To that I…