How atrazine affects development?

PLoS ONE paper The Herbicide Atrazine Activates Endocrine Gene Networks via Non-Steroidal NR5A Nuclear Receptors in Fish and Mammalian Cells will be one of the topics covered by Science Friday on NPR tomorrow - tune in if you can, or wait until the podcast is posted on the site later tomorrow night:

Researchers report that the common weedkiller atrazine may be able to disrupt hormonal signaling in humans. The herbicide is the second-most-applied weedkiller in the United States, with uses from suburban lawns to agricultural production of corn and sorghum.

In recent years, atrazine has been suspected of playing a role in sexual abnormalities in fish, frogs, and other aquatic organisms. The chemical has been banned in Europe, but is still widely used in the U.S. Now, writing in the journal PLOS One, researchers report that the chemical appears to affect two different genes in human placental cells. We'll talk with one of the authors of the study about the work and what it means.