Answer a Science Blogger

Stochastic, our master's voice, asks:

Assuming that time and money were not obstacles, what area of scientific research, outside of your own discipline, would you most like to explore? Why?

Well, of course it'd be

bioinformatics.

Why?

Interestingly technical, lots of data, wide open fundamental problems, impression that is is undersubscribed by researchers, both pure and applied problems, interdisciplinary.

I've seen some of the serious side of bioinfo related issues through my astrobiology hat, and it looks interesting and fun.

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Ooh! I'm applying for a course in that.

I'm coming from a maths background though, so I don't have a broad overview of the field. What would you say the major unsolved problems are?

Define "know how to program...", I have dabbled a bit in some code.

Seriously, I don't have a broad overview of the field, I have seen some interesting presentations on reconstructing ancestral gene sequences and and evolutionary trees, the different metrics, assumptions and priors.
From my perspective some interesting constraints were being ignored, I inferred for computational simplicity.

I've also always wanted to apply some of my active expertise to molecular modeling, in particular protein folding problems - problem is quite analogous to classical dynamics of self-gravitating systems with serious algorithm overlap and even same level of approximations. Again, lack of time, though we looked seriously at applications of mean field codes to molecular dynamics in background fluids, looked straightforward but computationally itensive.